This article details the five candidates in each party who raised the most money and lost their primary election. In the 2022 election cycle, 17 of 61 Republican primaries and 12 of 64 Democratic primaries were contested. The losing candidates are shown along with the percentage of the vote they received compared to the primary winner. In cases where the race was pushed to a runoff, vote percentages for both advancing candidates are included.

Democratic primary elections for all 67 districts in the Minnesota State Senate took place on Aug. 9, 2022. Of the 67 districts up for election in 2022, 12 had a Democratic primary election with more than one candidate.